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Famous Mississippi Pot Roast

A recipe for making the practically infamous slow cooker beef roast that took the Internet by storm! Delicious and fork tender, made with chuck roast, pepperoncinis and loads of seasonings.


  •     1 boneless chuck roast about 3 pounds.
  •     1 tablespoon salt
  •     1 teaspoon black pepper
  •     4 tablespoons flour
  •     3 tablespoons vegetable oil
  •     1 stick butter
  •     8 ounces pepperoncini pepper or more to your preference
  •     3 tablespoons mayonnaise
  •     1 tablespoon apple cider vinegar
  •     1 teaspoon dried dill
  •     1 teaspoon paprika
  •     1 teaspoon Worcestershire sauce
  •     1 teaspoon your favorite Louisiana style hot sauce
  •     1 teaspoon buttermilk optional


  1. Preheat oven to 250 degrees F.
  2. Season roast with salt, pepper and flour. Be sure to coat all sides.
  3. Heat the oil to medium heat in a large oven safe pot and sear the roast on one side for about 5 minutes, then flip and sear another 5 minutes. Sear the sides of the roast a couple minutes each as well.
  4. Remove from heat and add the butter and pepperoncinis. Let the butter melt.
  5. In a separate bowl, whisk together the mayonnaise, vinegar, dill, paprika, Worcestershire, hot sauce and buttermilk. Pour into the pot.
  6. Set the pot into the oven and cook for 5-6 hours, or until the meat is fork tender.
  7. Enjoy!
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