Skip to content

Culinary Guides

Famous Mississippi Pot Roast

by Organo Republic 21 Feb 2022

This is a recipe for the practically infamous slow cooker beef roast that took the Internet by storm! It's delicious and fork-tender, made with chuck roast, pepperoncini, and loads of seasonings.

Ingredients

  • 1 boneless chuck roast, about 3 pounds
  • 1 tablespoon salt
  • 1 teaspoon black pepper
  • 4 tablespoons flour
  • 3 tablespoons vegetable oil
  • 1 stick butter
  • 8 ounces pepperoncini peppers (or more to your preference)
  • 3 tablespoons mayonnaise
  • 1 tablespoon apple cider vinegar
  • 1 teaspoon dried dill
  • 1 teaspoon paprika
  • 1 teaspoon Worcestershire sauce
  • 1 teaspoon of your favorite Louisiana-style hot sauce
  • 1 teaspoon buttermilk (optional)

Directions

Prepare the Roast

  1. Preheat Oven:
    Preheat your oven to 250°F (120°C).
  2. Season and Coat:
    Season the chuck roast with salt and black pepper, then coat all sides evenly with flour.
  3. Heat Oil:
    Heat the vegetable oil over medium heat until hot in a large oven-safe pot.
  4. Sear the Roast:
    Place the chuck roast in the pot and sear for 5 minutes on each side, ensuring a deep golden-brown crust forms. Sear the sides of the roast for a couple of minutes each as well to lock in flavor.

Add Ingredients

  1. Add Butter and Pepperoncinis:
    Remove the pot from heat and add the stick of butter and pepperoncini peppers. Allow the butter to melt completely, coating the roast and peppers.
  2. Prepare Sauce:
    In a separate bowl, whisk together the mayonnaise, apple cider vinegar, dried dill, paprika, Worcestershire sauce, hot sauce, and buttermilk (if using). Mix until smooth and well combined.

Cook the Roast

  1. Pour Sauce:
    Pour the prepared sauce over the seared roast and pepperoncini in the pot.
  2. Cover and Cook:
    Cover the pot with a tight-fitting lid or aluminum foil and place it in the oven. Cook for 5-6 hours or until the meat is fork-tender and quickly pulls apart.

Serve

  1. Rest and Shred:
    Once cooked, remove the pot from the oven and let the roast rest for a few minutes. Then, using two forks, shred the meat directly in the pot, mixing it with the juices and sauce.
  2. Plate and Enjoy:
    Serve the Mississippi Pot Roast with your favorite sides, such as mashed potatoes, rice, or steamed vegetables. Drizzle the sauce over the top for extra flavor.

Additional Tips

  • Slow Cooker Option: If you prefer, transfer the seared roast and all ingredients to a slow cooker and cook on low for 8 hours or high for 4-5 hours.
  • Storage: Any leftovers can be stored in an airtight container in the refrigerator for up to 3 days. Reheat gently on the stovetop or in the microwave before serving.
  • Freezing: This pot roast can be frozen for up to 3 months. Allow it to cool completely before transferring it to a freezer-safe container. Thaw in the refrigerator overnight before reheating.
  • Serving Suggestions: This roast pairs wonderfully with mashed potatoes, rice, or crusty bread. For a delicious twist, you can also use the shredded meat in sandwiches or tacos.

Enjoy this comforting and flavorful Famous Mississippi Pot Roast, perfect for any cozy meal!

Prev post
Next post

Thanks for subscribing!

This email has been registered!

Shop the look

Choose options

Edit option
Compare
Product SKU Description Collection Availability Product type Other details
Terms & conditions

Choose options

this is just a warning
Login

Additional

Close

Your cart is empty

See More

21%
55 Vegetable Seeds Variety Pack

55 Vegetable Seeds Variety Pack

$29.99 $37.99
Add to Cart
34%
18 Culinary Herb Seeds Variety Pack

18 Culinary Herb Seeds Variety Pack

$16.99 $25.99
Add to Cart
35 Medicinal & Tea Herb Seeds Variety Pack

35 Medicinal & Tea Herb Seeds Variety Pack

$34.99
Add to Cart
26%
15 Medicinal & Tea Herb Seeds Variety Pack

15 Medicinal & Tea Herb Seeds Variety Pack

$16.99 $22.99
Add to Cart
Subtotal $0.00
Savings $0.00
Total $0.00
Checkout
Guarantee Easy Returns 30-day guarantee
$0.00 $0.00 $0.00